Christina Applegate Reveals MS Misdiagnosis, Battles Unidentified Illness
Actress Christina Applegate disclosed on October 20, 2026, that her previous diagnosis of multiple sclerosis (MS) was incorrect. The revelation came during an episode of her podcast, “MeSsy,” co-hosted with Jamie-Lynn Sigler. Applegate, who initially shared her MS diagnosis in August 2021, now faces an ongoing struggle with a mystery illness that mimics MS symptoms, leaving her feeling “back at square one.”
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